Abstract:Aim To investigate the relationship of central arterial pressure (CAP) and carotid intima-media thickness,cardiac hypertrophy. Methods 314 cases of patients with hypertension from January 2009 to October 2011 were chosen in the First Affiliated Hospital of Xinjiang Medical University. Those patients were checked for ankle-brachial pulse wave velocity, central aortic pressure, carotid intima-media thickness, and wall thickness. The subjects were divided into carotid intima-media thickness<0.9 mm group, and carotid intima-media thickness ≥0.9mm group. Subjects were divided into group with left ventricular hyperthrophy and group without left ventricular hypertrophy. To explore the correlation, BaPWV (pulse wave velocity), CSP (systolic blood pressure of central aortic pressure), CDP (diastolic blood pressure of central aortic pressure), CPP (pulse pressure of central aortic pressure), AP(augmentation pressure) were contrasted between the two groups. Results The BaPWV (pulse wave velocity), CSP (systolic blood pressure of central aortic pressure), AP(augmentation pressure), AIx (augmentation index), CPP(pulse pressure or central aortic pressure) were associated with carotid intima-media thickness, left ventricular hypertrophy, and the statistical comparison was significant (P<0.05). Conclusions The BaPWV (pulse wave velocity), CSP (central aortic systolic pressure), AP (increase pressure), AIx (augmentation index), CPP (central aortic pressure pulse pressure) may be associated with carotid intimal thickening and related cardiac hypertrophy.