Aim To explore the effect of gender on （brachial-ankle pulse wave velocity baPWV）. Methods Cross-sectional study was used in our study.We studied the baPWV of 5 440 workers in the Kailuan study cohort from 2006 to 2007,and 5 222 cases who took part in the third examination in 2010 to 2011 with complete data included in the final statistical analysis.Multiple linear regression and multiple logistic regression analysis were used to test the impact of gender on baPWV. Results The age adjusted mean value of baPWV was significantly higher in males than that in females（1570.19±300.53 cm/s vs 1507.93±301.27 cm/s,P<0.05）.After adjusting for age,systolic blood pressure,fasting blood glucose ,smoking,alcohol consumption and hypertension,diabetes mellitus,and other confounding factors,in the <60 age group baPWV was significantly higher in males than in females,and showed no difference between different genders in >60 year old group.In the <60 age group,after adjusted for age,low density lipoprotein cholesterol,fasting blood glucose,smoking,alcohol consumption and hypertension,female was an independent safety factor for baPWV accelerated ［OR（95%）0.74（0.59～0.93）］,compared with male. Conclusion The effect of age on baPWV are larger in females than in males.baPWV was lower in females than in males until age 60,and became similar in both genders over age 60.