Abstract:Aim To explore the changes of urine albumin and renal blood flow parameters and their relationship in the type 2 diabetic nephropathy patients with hypertension. Methods 75 cases of type 2 diabetic nephropathy patients with hypertension,according to urinary albumin excretion rate (UAER),were divided into 3 groups: microalbuminuria group,clinical proteinuria group and mass albuminuria group.30 healthy persons were as normal control group.Bloodstream spectrums of bilateral master renal arteries (MRA) and interlobar renal arteries (IRA) were detected by using color Doppler flow imaging (CDFI) and color Doppler energy imaging (CDEI).The detective indexes of various groups were compared,and the relationships between renal blood flow and UAER changes were analyzed. Results The pulsatile index and resistance index (RI) differences of both kidney in type 2 diabetic nephropathy patients with hypertension had statistical significance compared to normal control group (P<0.05).The pulsatile index and RI were increased with urine albumin excretion enhancing (P<0.05).Systolic Vmax,diastolic Vmin,RI,HAAC,and SAT of MRA and IRA in clinical proteinuria group,mass albuminuria group were markedly different from those in normal control group.Pearson correlation analysis showed that the Vmax,Vmin and RI of MRA and IRA had significant correlation with UAER. Conclusion Renal arteries blood flow indexes detected by CDFI and CDEI can provide an important basis for the early diagnosis and evaluation of prognosis of clinical diabetic nephropathy.