Aim To compare the one-year outcome of homemade durable drug-eluting stents （Partner） with bioabsorbable drug-eluting stents （Excel） in patients undergoing percutaneous coronary intervention （PCI）. Methods Patients with coranary heart disease were simultaneously received Partner and Excel stents implantation in different coronary arteries.PCI characteristics,clinical symptoms and coronary angiography after one year were analyzed. Results From December 2010 to April 2013,202 patients were treated with Partner and Excel stents simultaneously in different vascular.Finally,107 patients were involved in this study.The average length of stents were 26.4±12.4 mm vs 28.2±11.5 mm （P>0.05）,the average diameter of stents was 3.035±0.455 mm vs 3.076±0.432 mm （P>0.05）.There were no acute myocardiac infarction and stent thrombosis occurred.The restenosis rates were 8.4% in Partner group and 7.5% in Excel group resperctively （P>0.05）.No difference was observed in the changes of side branches. Conclusion In this “real-world” study,the followup outcomes were similar between homemade durable DES （Partner） and bioabsorbable DES （Excel）.