Abstract:Aim To evaluate the left ventricular systolic and diastolic function by automated motion tracking of mitral annular displacement (TMAD) in patients with coronary heart disease (CHD).Methods Twenty-seven CHD patients (group CHD) confirmed by coronary angiography and thirty age-matched normal controls were enrolled in this study.The parameters were obtained by TMAD which lasted at least three consecutive cardiac cycles: maximal systolic displacement (Ds),early diastolic displacement (De) and late diastolic displacement (Da) of the four points of mitral annulus,the time to peak systolic displacement (T),systolic displacement of the middle point (Mid) and its ratio to the length of left ventricle at end-diastole (Mid%),then separately to calculate the mean of foregoing numbers.And the Da/Dt ratio was calculated (Dt=De+Da).Then,the correlation between the mean of Ds,the mean of Mid,the mean of Mid% and left ventricular ejection fraction (LVEF) measured by biplane Simpson methods,between Da/Dt ratio and transmitral index E/A ratio were analyzed.Results (1)Compared with control group,the Ds,Mid,Mid% of four points,the mean of Ds,the mean of Mid and the mean of Mid% were decreased significantly (all P<0.01),the T of four points and the mean of T increased significantly (P<0.05 or P<0.01) in group CHD.(2)Compared with control group,the De of four points and the mean of De were decreased significantly (all P<0.01),the Da of lateral,anterior and inferior mitral annulus,the mean of Da of four points (P<0.05 or P<0.01) and Da/Dt ratio (P<0.01) increased significantly in group CHD.(3)In both two groups,the mean of Ds,the mean of Mid and the mean of Mid% show a positive correlation to LVEF (control group: r=0.697,r=0.711,r=0.779,P<0.01 group CHD: r=0.707,r=0.703,r=0.789,P<0.01).(4)In both two groups,Da/Dt ratio show a positive correlation to A/E ratio (control group: r=0.739,P<0.01 group CHD: r=0.666,P<0.01).Conclusion TMAD can access the left ventricular function in patients with CHD objectively and expediently.