Aim To detect the correlation between hyperuricemia (HUA) and chronic heart failure. Methods We selected 422 patients with CHF (260 with HFpEF) and 134 patients without CHF hospitalized in Shengjing Hospital of China Medical University between February 2009 and January 2012. The correlation between HUA and CHF was analyzed with t inspection, χ2 inspection and Logistic analysis and the prognostic correlation between them was further explored through Follow-up studies. Results Serum UA in HFpEF and HFrEF group (374.54±144.30 μmol/L, 416.45±168.93 μmol/L) was significantly higher than non-heart failure group (299.71±114.36 μmol /L, P<0.05).