Aim The aim of this study was to establish the accuracy of transthoracic echocardiography (TTE) in diagnosis of acute aortic dissection type Stanford A. Methods A total of 35 cases of acute aortic dissection type Stanford A were retrospectively analyzed, who underwent both transthoracic echocardiography and CTA. Results The diagnostic accuracy of TTE and CTA of acute aortic dissection type Stanford A were 91.3% and 100%, respectively. However, TTE could show aortic valve abnormalities, heart function, pericardial effusion. Conclusion TTE is a reliable method for diagnosis of acute aortic dissection type Stanford A. The pivotal role of TTE in the evaluation of the patients with suspected acute type A aortic dissection in emergency room setting.