冠状动脉支架对完全闭塞与非闭塞病变的疗效比较
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广东省科委科技攻关基金(9827803)资助


Angiographic and Clinical Outcomes of Stenting for Totally Occluded Versus Nonoccluded Coronary Arteries
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    摘要:

    为比较冠状动脉支架对完全闭塞与非闭塞病变的即时结果和长期疗效,对5 16例(6 87处病变)行冠状动脉支架术的患者进行分析。将患者按手术部位的阻塞程度分为完全闭塞组(142例,16 0处病变)和非闭塞组(374例,5 2 7处病变) ,观察两组患者行冠状动脉支架术后的即时疗效及临床和造影复查的结果。结果显示:完全闭塞组术前血管最小腔径显著小于非闭塞组(P<0 .0 0 1) ,而术后两组没有统计学差异;临床并发症两组差异无显著性,影像学并发症完全闭塞组显著高于非闭塞组(6 .1%比2 .5 %,P<0 .0 5 ) ;完全闭塞组2 7.8%的病变可见再狭窄,非闭塞组2 3.7%的病变可见再狭窄,两组比较无显著性差异;随访临床事件:完全闭塞组2 5 .2 %,非闭塞组2 2 .7%,两组比较无显著性差异。以上结果表明冠状动脉支架对冠状动脉完全闭塞病变的即时结果和长期疗效均与非闭塞病变相近。

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    Aim To compare the immediate and long-term outcomes of coronary stenting for total occlusions with nonocclusive stenoses. Methods A total of 516 consecutive patients (687 lesions) underwent coronary stenting. The study population was divided into total occlusion group (TO group, 142 patients with 160 lesions) and non-occlusion group (NO group, 374 patients with 527 lesions). The immediate and long-term angiographic and clinical outcomes were assessed. Results There was no difference in postprocedure minimum lumen diameter (3.12±0.51 vs. 3.13±0.54 mm, p>0.05) between TO and NO groups. There was no difference in incidence of clinical complications between the two groups. A total of 27.8% of patients in TO group and 23.7% of lesions in NO group occurred restenosis (p>0.05). Clinical events occurred in 25.2% of patients in TO group compared with 22.7% in NO group (p>0.05). Conclusions The immediate and long-term outcomes of coronary stenting for total occlusions are comparable to that for nonocclusive stenoses.

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杜志民,罗初凡,胡承恒,李怡,曾武涛,马虹.冠状动脉支架对完全闭塞与非闭塞病变的疗效比较[J].中国动脉硬化杂志,2003,11(5):443~445.

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  • 收稿日期:2002-11-25
  • 最后修改日期:2003-05-30
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