Aim To evaluate the relationship between blood pressure and the range and severity of coronary artery stenosis. Methods 540 inpatients who had been diagnosed with suspicious coronary heart disease(CHD) were carried through coronary angiography.Blood pressure and blood lipoprotein of all patients were measured.Their history of high blood pressure,smoking and diabetes was investigated.All patients were carried with angiography by Judkins way.Based on coronary artery lesion 540 inpatients were separated into two groups: lesion group and no lesion group;based on coronary artery lesion range 540 inpatients were separated into three groups: single vessel disease group,double vessel disease group and triple vessel group. Results Coronary angiography shows that patients in lesion group have more hypertension history(5.85 ±8.87 years),higher level of systolic blood pressure(133±29 mm Hg),diastolic blood pressure(83±13 mm Hg),pulse pressure(51±17 mm Hg) and mean blood pressure(100±14 mm Hg) than that in no lesion groups(1.78±4.27 years,125±21 mm Hg,80±13 mm Hg,48±15 mm Hg and 97±15 mm Hg). There were more hypertension history,higher level of systolic pressure and pulse pressure in single vessel disease group and triple vessel group(7.42±10.10 years,137±21 mm Hg and 54±17 mm Hg) than that in single vessel disease group(4.51±7.21 years,132±19 mm Hg and 49±16 mm Hg),and double vessel disease group(5.76±8.79 years,134±23 mm Hg and 52±17 mm Hg).Difference among three groups had noticeable significance(p<0.05).Severity of coronary artery stenosis was developed with more hypertension history,higher level of systolic blood pressure,pulse pressure and mean blood pressure.Hypertension(OR=0.139,p<0.05),and ages(OR=1.045,p<0.05) were independent risk factors for happening of coronary artery disease by multiple factor regression analysis. Conclusions Opportunity of coronary artery disease was increased with ages and hypertension history.Moreover,higher level of systolic blood pressure and pulse pressure were more harmful than others.