Aim To discuss the relationship between the pulse wave velocity and coronary atherosclerosis. Methods 104 patient were selected, all patients were underwent coronary arteriongraphy or interventional therapy, and pulse wave velocity, blood biochemistry examination, history-taking were measured to analyze the serious degree relationship between pulse wave velocity and coronary artery disease. Results Age and PWV and pulse pressure were significant risk factor of coronary atherosclerosis. Age, PWV, pulse pressure, hypertensive history systolic blood pressure, smoking and cholesterol have significant difference in coronary artery disease extent. According to the grouping of largest narrow degree of coronary artery disease, there is significant difference between narrow degree 1, 2, 3, 4 and 0 in severity of coronary heart disease; between narrow degree 1 and 2 there is significant difference. Comparing patients with PWV≤14.02 m/s and PWV>14 m/s, there is significant difference in severity ofcoronary artery. Patients with PWV>14 m/s had higher incidence of 3 disease. There is no difference between patients with essential hypertension and those without hypertensios. PWV may reflect kinds of risk factor to vascul damages. Conclusions There are dependablities about PWV and coronary artery disease severity degree. Detecting PWV can be used to evaluate the coronary artery disease danger hierarchication,and it can identify the coronary artery severity extent.