Aim To evaluate the clinical effects of amlodipine on arterial elasticity and left ventricular hypertrophy in elderly hypertensive patients. Methods The arterial elasticity indexes of the hypertensive patients(76 cases) were detected with CVP rofilor DO-2020,and left ventricular mass indexes were measured with ultrasound cardiography before and after long-term (36 months) treatment with amlodipine. Results the blood pressure was controlled to therapeutic aim and maintained stable after 8 weeks treatment with amlodipine. The small artery elasticity index rised significantly than that after 36 months treatment with amlodipine (2.60±0.77 mL/Pa vs 3.80±2.09 mL/Pa, P<0.01); and the left ventricular mass indexes reduced dramatically than that after therapy (147.3±26.8 g/m2 vs 131.7±24.3 g/m2,P<0.01). Conclusion Amlodipine can improve arterial eladticity and vascular function,retard or even reverse left ventricular hypertrophy,while lowering blood pressure stably.