Aim To analyse risk factors of intracranial vascular stenosis in patients with cerebral infarction. Methods 186 patients with cerebral infarction were assessed by transcranial Doppler.Uric acid(UA) and lipids including total cholesterol(TC),low density lipoprotein cholesterol(LDLC),high density lipoprotein cholesterol(HDLC) and triglyceride(TG) were examined. Results TC(5.04±1.23 mmol/L) and LDLC(2.99±1.01 mmol/L) were significantly higher in patients of stenosis group compared with nonstenosis group(4.60±1.12 mmol/L and 2.59±0.69 mmol/L respectivly,P<0.05).Pearson analysis showed that intracranial vascular stenosis correlated with hypertension(r=0.206,P=0.005),diabetes(r=0.238,P=0.001),TC(r=0.181,P=0.016),LDLC(r=0.227,P=0.003) and UA(r=0.132,P=0.016).Significant independent predictors of intracranial vascular stenosis by multivariate analysis included hypertension(OR=2.345,P=0.026),diabetes(OR=2.554,P=0.024),LDLC(OR=1.764,P=0.009) and UA(OR=1.006,P=0.007). Conclusions Except for hypertension and diabetes,UA and LDLC might be independent predictors of intracranial vascular stenosis in patients with cerebral infarction.