Aim By studying intravascular ultrasound(IVUS),coronary angiography (CAG) and the results of carotid body ultrasonic testing of carotid artery disease to analyze the relationship between carotid atherosclerosis and coronary heart disease,to further explore carotid atherosclerosis on the predictive value of coronary heart disease.Methods 38 cases of initial diagnosis for patients with coronary heart disease accepted CAG and IVUS examination,surface carotid artery ultrasound testing.8 patients with no significant coronary artery stenosis (non-coronary heart disease) were used as the control group;30 cases with significant coronary artery stenosis were divided into groups of coronary heart disease,including 18 cases of unstable angina pectoris (UAP) and 12 cases of stable angina pectoris (SAP).The results of carotid ultrasound indicators,CAG and IVUS examination were analyzed and compared.Results The average diameter stenosis rate of CAG was 71.21%±9.81% in 30 cases with coronary heart disease.IVUS showed that 30 cases of coronary heart disease in patients with different types of atherosclerotic plaque and the average rate of the narrow area was 80.88%±7.77%;There were significant difference between the average diameter stenosis rate of CAG and the average rate of the narrow area of IVUS (P<0.01);They also had significant correlation between the two indicators (r=0.663,P<0.01).It prompted that CAG underestimated the degree of stenosis of coronary lesions to some extent compared with IVUS.The coronary Gensini integral according to the calculation of CAG had a significant correlation with the carotid atherosclerosis grade integral,Crouse integral,plaque volume(P<0.01).Carotid artery plaque on the positive predictive value of coronary heart disease was 70%(21/30)and the negative predictive value was 75%(6/8).Conclusion It canclearly show the coronary artery wall structure and accurately diagnose coronary artery plaque on the nature,accurately measure the rate of coronary artery stenosis by application of the IVUS imaging.IVUS assessment of coronary artery disease is more accurate compared with CAG.There are very good correlation between the carotid atherosclerosis and the severity of coronary artery IVUS results.Carotid ultrasound detection has some predictive value to coronary heart disease.