AimTo investigate the feasibility and the clinical value of strain-blood pressure index (SBPI) in assessing the elasticity of brachial artery and anterior tibial artery in patients with end-stage renal disease (ESRD).Methods39 patients with ESRD and 46 healthy volunteers were involved.39 patients with ESRD belonged to the case group,and 46 healthy volunteers belonged to the control group.Maximum of circumferential strain(CSmax) of brachial artery and anterior tibial artery were acquired through strain and strain rate imaging(Xstrain).Local blood pressure which included local systolic blood pressure(LSBP) and local diastolic blood pressure(LDBP) of brachial artery and anterior tibial artery were measured at the same time.SBPI were calculated.Parameters were compared between the case group and the control group.ResultsSBPI of anterior tibial artery in case group (4.01％±0.59％) was less than that in control group(5.71%±0.55%,p<0.01).While SBPI of brachial artery in case group and control group were 3.82％±0.39％ and 3.95％±0.46％ respectively.There was no significant difference between case group and control group(p>0.05).ConclusionSBPI might be a new index that could evaluate the elasticity of medium-sized arteries in patients with ESRD.