Abstract:Aim To explore whether the use of peripheral arterial tonometry (PAT) in the evaluation of admission vascular endothelial function of acute myocardial infarction (AMI) patients can predict recurrence of major adverse cardiovascular events (MACE). Methods For 116 consecutive patients clinically diagnosed with AMI received evaluation of vascular endothelial function using PAT technique within 72 hours of admission, reactive hyperemia index (RHI) was calculated. By the cut point of normal RHI (1.67) patients were divided into the normal endothelial function group (RHI≥1.67) and the endothelial dysfunction group (RHI<1.67), follow-up of MACE was conducted in both groups during hospitalization (median value 8.0 days) and after discharge from hospital (243.8±68.3 days). MACE included cardiac death, recurrent acute myocardial infarction, recurrent unstable angina during hospitalization, ischemic stroke, elective percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), and hospitalization due to cardiovascular causes. Result There was no significant difference in recurrence of MACE between PAT-determined endothelial dysfunction group (RHI<1.67) and normal endothelial function group (RHI≥1.67) both during hospitalization and after discharge from hospital (P=0.098 and 0.104, respectively). Conclusion PAT cannot predict recurrence of major adverse cardiovascular events in AMI patients both during hospitalization and after discharge from hospital.