AimTo investigate the risk factors of cerebral infarction in cancer patients.Methods67 cases of tumor patients with cerebral infarction were included as the tumor group who were treated in hospital from January 2005 to August 2012, 67 cases of general cerebral infarction were randomly selected at the same times as control group.The difference was analysed between tumor group and control group in hypertension, diabetes, hyperlipidemia,plasma fibrinogen and D- dimmer.ResultsIncidence of hypertension, diabetes and hyperlipidemia was significantly lower in tumor group (P<0.05 or P<0.01)， D-dimmer and fibrinogen level was significantly higher than that of contrl group ( P<0.05 or P<0.01).Multivariate regression analysis showed that plasma fibrinogen and D-dimmer were the risk factors of cerebral infarction in cancer patients.ConclusionsStroke risk factors are different between the cancer patients and general people.Cancer-associated hypercoagulation is an important stroke risk factor in patients with cancer.