脑梗死并高血压病患者颈动脉硬化与左心室功能的相关性
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The Correlation Between Atherosclerosis on Carotid Artery and the Function of Left Ventricular in Cerebral Infarction Combined Hypertension Patients
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    目的 探讨脑梗死并高血压病患者颈动脉粥样硬化与左心室收缩及舒张功能的相关性。方法 收集单纯高血压病患者100例(高血压组)、单纯脑梗死患者100例(脑梗死组)、脑梗死合并高血压病患者100例(合并组)的颈动脉粥样硬化和左心室收缩及舒张功能的相关超声学指标资料,其中收缩功能指标为射血分数,舒张功能指标为二尖瓣血流图上早期充盈的E峰和晚期充盈的A峰血流速度的比值(简称E/A比值),采用Logistic回归分析探讨它们的相关性。结果 3组患者颈动脉粥样硬化与左心室收缩功能均无相关性(P>0.05),与左心室舒张功能有相关性((P<0.05),且合并组斑块形成与左心室舒张功能相关性更显著((P<0.01)。结论 3组患者颈动脉粥样硬化与左心室舒张功能相关,合并组的相关性更明显;左心室舒张功能受损越严重,动脉粥样硬化程度越明显。

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    Aim To research the correlation between atherosclerosis on carotid artery and the systolic and diastolic function of left ventricular in cerebral infarction combined hypertension patients. Methods The study collected ultrasonic indexs of atherosclerosis on carotid artery and left ventricular systolic and diastolic function in 100 hypertension patients (abbreviated group of hypertension), 100 cerebral infarction patients (abbreviated group of cerebral infarction) and 100 cerebral infarction combined hypertension patients (abbreviated group of combination). Ejection fraction (EF) was used as systolic function index, ratio of blood flow velocity between early filling of E peak and late filling A peak (E/A) on flow chart of mitral was used as diastolic function index. Logistic regression analysis was used to explore the correlation in themselves. Results There aren’t correlations between atherosclerosis on carotid artery and the systolic function of left ventricular in the three groups of patients (P>0.05). However there are correlations between atherosclerosis on carotid artery and the diastolic function of left ventricular in the three groups of patients (P<0.05). And the correlation between the form of carotid atherosclerotic plaque and diastolic function of left ventricular in group of combination is more significant than in other groups (P<0.01). Conclusions Atherosclerosis on carotid artery is related with the diastolic function of left ventricular in the three groups of patients. Moreover it is most obvious in the group of combination. The more serious damage of left ventricular diastolic function, the more obvious arteriosclerosis on carotid artery.

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李建刚,杨金锁.脑梗死并高血压病患者颈动脉硬化与左心室功能的相关性[J].中国动脉硬化杂志,2013,21(09):841~844.

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  • 收稿日期:2012-12-14
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