Abstract:Aim To research carotid intima-media thickness (IMT) and elasticity and blood lipid levels in patients with pregnancy-induced hypertension (PIH). Methods 98 women with pregnancy were divided into 2 groups: 48 patients with pregnancy induced hypertension for research group (PIH group), 50 women with pregnancy that age and gestational weeks were matched for control group. To evaluate carotid IMT, pulse wave velocity (PWV), pressure at T1 (PT1), augmented pressure (AP) and augmentation index (AIx) in patients ultrasound radio-frequency data (RF-data) technology was used. Serum total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDLC), low density lipoprotein (LDLC ), apolipoprotein A1 (ApoA1) and apolipoprotein B100 (ApoB100) were detected and compared in each group. Results Compared with the control group, pregnant women’s test value of IMT and PWV, PT1, AP and AIx of PIH group increased, TC, TG, LDLC, ApoB100 increased, and HDLC, ApoA1/ApoB100 decreased in late pregnancy. The differences were statistically significant (all P<0.05). After 6 months postpartum, TRIG increased and ApoA1/ApoB100 decreased compared with the control group (all P<0.05). The differences of other indexes had no statistical significance (P>0.05). The correlation between IMT and blood pressure and blood lipid metabolism shows,the IMT and the blood pressure and blood lipid metabolism of each index (exception of ApoB100) all have close correlation (P< 0.05). Conclusions PIH women had change of the carotid arterial structure and elasticity and blood lipid metabolism disorder in late pregnancy. But after 6 months postpartum,the carotid structure and elasticity recovered. Lipid metabolism returned to almost normal level. Blood lipid metabolic abnormalities caused vascular elasticity and the function of change may be the cause of PIH occurred.