肥胖对高血压患者血压变异性的影响
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Effect of Obesity on Blood Pressure Variability in Patients with Hypertension
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    摘要:

    目的 评估肥胖对原发性高血压患者血压变异性(BPV)的影响。方法 选择2014年1月至2014年4月我院就诊的单纯性高血压患者159例,根据腹围和体质指数(BMI)分别分组,进行24 h动态血压监测(ABPM),观察BPV特点。结果 按照体质指数分组,观察组(BMI≥28 kg/m2,男性40例,女性40例)24 h平均收缩压变异系数、日间平均收缩压变异系数高于对照组(BMI<28 kg/m2,男性43例,女性36例),差异有统计学意义(P<0.05);两组男性患者夜间平均收缩压变异系数、夜间平均舒张压变异系数均高于女性患者(P<0.05),且观察组男性患者24 h平均收缩压变异系数高于女性患者(P<0.05)。按照腹围分组,观察组(男性腹围≥90 cm 45例,女性腹围≥85 cm 42例)24 h平均收缩压变异系数、日间平均收缩压变异系数高于对照组(男性腹围<90 cm 38例,女性腹围<85 cm 34例),差异有统计学意义(P<0.05),两组男性患者夜间平均舒张压变异系数高于女性患者(P<0.05),且观察组男性患者24 h平均收缩压变异系数高于女性患者(P<0.05)。结论 肥胖时,高血压患者BPV增高,且男性患者较女性患者明显,提示在控制血压的同时,还应注意调节BPV,特别是男性肥胖患者。

    Abstract:

    Aim To explore the effect of abdominal obesity on blood pressure variability (BPV) in patients with primary hypertension. Methods A total of 159 patients who were admitted to our hospital because of simple hypertension were enrolled in this study and divided into two parts respectively based on body mass index (BMI) and abdominal circumference (AC). For part 1, patients were divided into normal BMI group (BMI <28 kg/m2, n79) and high BMI group (BMI≥28 kg/m2,n80) for part 2, patients were divided into normal AC group (male<90 cm, female<85 cm, n72) and high AC group (male≥90 cm, female≥85 cm, n87). And the characteristics of their BPV were observed respectively through 24 hour ambulatory blood pressure monitoring (ABPM). Rseults The coefficients of variation (CV) of both the 24 hour mean systolic blood pressure and daytime mean systolic blood pressure of the observation group (BMI≥28 kg/m2, n87) were higher than those of the control group (BMI <28 kg/m2, n79), and there were statistically significant differences between the observation group and the control group (P<0.05 ). The CV of nighttime mean systolic and diastolic blood pressures of male patients in both the observation group and the control group were higher than those of female ones in the two groups, and the differences were statistically significant (P<0.05). In the observation group, the CV of 24 hour mean systolic blood pressure of male patients were higher than that of female ones, and the differences were statistically significant (P<0.05). The CV of both the 24 hour mean systolic blood pressure and the daytime mean systolic blood pressure of patients of the observation group (AC of male≥90 cm, AC of female≥85 cm, n87) were higher than those of the control group, and the differences were statistically significant (P<0.05). The CV of nighttime mean diastolic blood pressure of male patients of both the observation and the control groups were higher than that of female ones of the two groups, and the differences were statistically significant (P<0.05). In the observation group, the CV of 24 hour mean systolic blood pressure of male patients were higher than that of the female ones, and the differences were statistically significant (P<0.05). Conclusions Their BPV will increase when the patients with hypertension have abdominal obesity. And this effect is more obvious in male patients than that in female ones. So more attetion should be paid by doctors to the regulation of BPV among patients with hypertension, especially male ones with abdominal obesity, as controling the patients’ blood pressure.

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曾琳琳,刘振良,李萃萃,胡立禄,张成伟,毕松杰,尹 锐,钟新荣.肥胖对高血压患者血压变异性的影响[J].中国动脉硬化杂志,2015,23(06):617~620.

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  • 收稿日期:2014-07-11
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