Abstract:Aim To explore the correlation of elasticity change between carotid artery and femoral artery in patients with high-normal blood pressure. Methods Intima-media thickness (IMT) in the bilateral carotid artery and femoral artery was measured by two-dimensional ultrasound in 76 patients (including male 42 cases and female 34 cases,mean age 47.56±10.54 years old) with high-normal blood pressure and 50 cases of normal control group (including male 26 cases and female 24 cases,mean age 48.16±11.17 years old),carotid artery and femoral artery elastic parameters of β,Ep,arterial compliance (AC) and pulse wave velocity (PWV) were detected by echo tracking technology,and correlation of carotid artery and femoral artery was analyzed. Results Compared with normal control group,β,Ep,PWV of carotid artery and femoral artery were increased conspicuously in high-normal blood pressure group (P<0.001),AC was lower significantly in high-normal blood pressure group (P<0.001).There was no difference in IMT of carotid artery and femoral artery between the two groups respectively (P>0.05).The correlation coefficients of β,Ep,PWV in carotid artery and femoral artery in patients with high-normal blood pressure were 0.354,0.304 and 0.360 (P<0.001),which was a significant positive correlation.There were no significant correlation of IMT and AC between carotid and femoral artery (r=0.108,P=0.184 r=0.114,P=0.163). Conclusion The carotid and femoral artery elasticity decreased and involved simultaneously before the artery IMT had ultrasonic morphological change.