原发性高血压患者踝臂指数、肱踝脉搏波传导速度与心脏结构、功能改变的相关性
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The Correlation Between Ankle Brachial Index,Brachial-Ankle Pulse Wave Velocity and Cardiac Structure and Function in Patients with Essential Hypertension
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    摘要:

    目的 探讨原发性高血压患者踝臂指数(ABI)、肱踝脉搏波传导速度(BaPWV)与心脏结构、功能改变的相关性。方法 收集新疆医科大学第一附属医院干部病房内二科2013年8月~2014年10月符合入选标准的151例高血压患者,询问病史、体检、测血压并进行全自动动脉硬化测试仪(VP-1000)和超声心动图检查及生物化学检测,分别按ABI和BaPWV分两组:ABI低值组和ABI正常组,BaPWV增高组和BaPWV正常组。结果 (1)ABI低值组室间隔厚度(IVST)明显大于ABI正常组(P<0.05)。与ABI正常组比较,ABI低值组左心室射血分数(LVEF)、A峰、E峰流速比值(E/A)均明显减低(P<0.05)。BaPWV增高组左心房前后径(LAD)、IVST明显大于BaPWV正常组(P<0.05)。BaPWV增高组LVEF小于BaPWV正常组(P<0.05)。(2)相关分析显示,ABI与IVST呈负相关(r=-0.769,P<0.05),与LVEF、E/A呈正相关(r值分别为0.668、0.566,P<0.05)。BaPWV与LAD、IVST呈正相关(r值分别为0.331、0.474,P<0.05),与LVEF呈负相关(r=-0.526,P<0.05)。结论 ABI和BaPWV与原发性高血压患者心脏结构、功能改变呈显著相关,可为临床医生进行尽早干预治疗提供信息。

    Abstract:

    Aim To investigate the correlation between ankle brachial index (ABI),brachial-ankle pulse wave velocity (BaPWV) and cardiac structure and function in patients with essential hypertension. Methods The study was performed on 151 hypertension patients who meet the criteria in the First Affiliated Hospital of Xinjiang Medical University from August 2013 to October 2014. These selected patients were inquired for case history and given physical examination,the blood pressure,automatic arteriosclerosis tester(VP-1000),cardiac ultrasound and blood biochemistry detection. According to the value of ABI and BaPWV,all patients were divided into two groups: low ABI group and normal ABI group,high BaPWV group and normal BaPWV group. Results (1) Interventricular septal thickness(IVST) in low ABI group was significantly higher than those in normal ABI group(P<0.05). Compared with normal ABI group,left ventricular ejection fraction(LVEF) and blood flow peaks E and A ratio(E/A) in low ABI group were obviously reduced(P<0.05) Left atrium diameter(LAD) and IVST in high BaPWV group were higher than those in normal BaPWV group(P<0.05). LVEF in high BaPWV group was lower than those in normal BaPWV group (P<0.05). (2)Correlation analysis revealed that there was negetive correlation between ABI and IVST(r=-0.769,P<0.05),positive correlation between ABI and LVEF,E/A(r 0.668,0.566,P<0.05). There was positive correlation between BaPWV and LAD,IVST(r0.331,0.474,P<0.05),negative correlation between BaPWV and LVEF(r=-0.526,P<0.05). Conclusion There was a significant correlation between ABI,BaPWV and cardiac structure and function in patients with essential hypertention,which can provide information for clinical doctors,early intervention treatment.

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布热比艳·太来提,布娃加·吾守尔,玛依努尔·伊明艾山,李亚楠.原发性高血压患者踝臂指数、肱踝脉搏波传导速度与心脏结构、功能改变的相关性[J].中国动脉硬化杂志,2015,23(09):902~906.

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  • 收稿日期:2014-11-21
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  • 在线发布日期: 2015-07-21