Aim To study the association between H-type hypertension and coronary slow flow （CSF） in patients undergoing PCI therapy with acute myocardial infarction. Methods 120 patients with hypertension and acute myocardial infarction which accepted the emergency treatment of PCI in our hospital from January 2013 to July 2014 were enrolled as the research subjects. According to the blood flow level presented during the PCI therapy, these cases were divided into CSF group （27 cases） and non-CSF group （93 cases）. Blood lipid level, high sensitivity C-reactive protein （hs-CRP） and plasma homocysteine were tested and compared between the two groups, so did the proportion of patients with H-type hypertension. The risk factors of CSF were screened by Logistic regression analysis. Results In CSF group, the proportion of patients with H-type hypertension was significantly higher than that in non-CSF group （P<0.05）. With Logistic regression analysis, H-type hypertension was found to be a significant risk factor of CSF. Conclusion H-type hypertension is closely related to the CSF in patients with acute myocardial infarction which undergo primary PCI treatment.