中老年人群理想心血管健康评分变化和踝臂指数的关系
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(1.开滦总医院物理诊断科,;2.唐山市传染病院功能检查科,;3.华北理工大学附属医院超声科,;4.开滦总医院心内科,河北省唐山市 063000)

作者简介:

刘雪梅,硕士研究生,主任医师,研究方向为心血管超声诊断,E-mail为kaidongliu102@sina.com。

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国家科技支撑计划项目(2008BAI52B03)


Relationship Between Change of Ideal Cardiovascular Health Score and Ankle Brachial Index in Elderly Population
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1.Department of Physical Diagnosis, Kailuan General Hospital, ;2.Department of Function Inspection, Tangshan Hospital for Infectious Diseases, ;3.Department of Ultrasonography, Affiliated Hospital of North China University of Science and Technology, ;4.Department of Cardiology, Kailuan General Hospital, Tangshan, Hebei 063000, China)

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    摘要:

    目的 探讨中老年人群理想心血管健康评分变化(△ICHS)与踝臂指数(ABI)的关系。方法 在101510名参加2006-2007年开滦集团职工体检者中,随机分层抽取5852人作为研究对象,其中符合入选标准者5440例。每2年1次体检,并于2010-2011年再次体检时增加ABI。去除数据缺失者,最终纳入统计分析的研究对象为4524例。按照美国心脏协会提出的7项心血管健康指标,将人群进行理想心血管健康评分(ICHS)。根据2006-2007、2010-2011年2次体检的△ICHS,采用线性回归和Logistic回归分析△ICHS与ABI的关系。结果 随着△ICHS由低向高转变,△收缩压、△舒张压、△体质指数、△总胆固醇及△空腹血糖均呈逐渐下降趋势(P<0.05),理想食盐习惯和体育锻炼人群比例明显改善,分别升高了9.3%和17.2%,理想吸烟人群比例下降约4.6%。总人群的收缩压、舒张压、体质指数、总胆固醇及空腹血糖均较基线时略有升高。ABI随△ICHS升高呈逐渐升高趋势(P<0.05)。线性回归结果显示:△ICHS与ABI呈正相关,在校正多种混杂因素之后,△ICHS每增加1分,ABI升高0.004(B值:0.004,P=0.004)。Logistic回归分析也显示:在校正多种混杂因素之后,与ICHS降低组相比较,ICHS不变组和ICHS升高组的ABI异常呈下降趋势,△ICHS每增加1分,ABI异常风险降低约21%(OR:0.79,95%CI:0.68~0.91)。结论 △ICHS与ABI呈正相关。△ICHS是中老年人群动脉硬化的独立预测因素。

    Abstract:

    Aim To explore the relationship between change of ideal cardiovascular health score (△ICHS) and the ankle-brachial index (ABI) in the elderly population. Methods Through stratified random sampling, a total of 5852 cases were enrolled from 101510 Kailuan Group employees who participated in the health examination in 2006-2007, and among which 5440 individuals met the inclusion criteria. 1 physical examination every 2 years, and ABI was measured by ultrosoud in 2010-2011 examination. Excluding the incomplete data, 4524 cases were included for the final analysis. Ideal cardiovascular health score (ICHS) was performed in the population, according to the 7 cardiovascular health indexes proposed by the American Heart Association. According to the △ICHS of 2006-7,0-2011 examination, the relationship between △ICHS and ABI was analyzed by linear regression and Logistic regression. Results With the △ICHS changed from low to high, △SBP, △DBP, △BMI, △TC and △FBG all decreased (P<0.05). The proportions of ideal salt habit and physical exercise population significantly increased by about 9.3% and 17.2% respectively, and the proportion of ideal smoking population decreased by about 4.6%. SBP, DBP, BMI, TC and FBG were slightly higher than that in baseline. With the increase of △ICHS, ABI gradually increased (P<0.05). Linear regression analysis showed that △ICHS was positively related with ABI, and after adjusting for various confounding factors, the △ICHS increased by 1 point, ABI increased by 0.004 (B=0.004, P=0.004). Logistic regression analysis showed that after adjusting for various confounding factors, compared with the ICHS reducing group, the ABI abnormality of ICHS invariant group and ICHS elevating group revealed a downward trend. The △ICHS increased by 1 point, abnormal ABI risk reduced by about 21% (OR:0.9,5%CI:0.68-0.91). Conclusions △ICHS is positively correlated with ABI. △ICHS is an independent predictor of atherosclerosis in the elderly population.

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刘雪梅,黄玮,聂维齐,邵丹,李晓庆,张莹,吴寿岭.中老年人群理想心血管健康评分变化和踝臂指数的关系[J].中国动脉硬化杂志,2016,24(10):1044~1049.

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  • 收稿日期:2015-06-30
  • 最后修改日期:2015-09-14
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  • 在线发布日期: 2016-10-13