短暂性单眼视野缺损眼部动脉血流动力学改变及颅内段颈内动脉狭窄特点
DOI:
作者:
作者单位:

(首都医科大学附属北京友谊医院放射科,北京市 100050)

作者简介:

李瑞,硕士,住院医师,研究方向为头颈影像,E-mail为1120097968@qq.com。

通讯作者:

基金项目:

北京市医管局临床医学发展专项“扬帆”计划(XMLX201305) [人才项目]北京市医管局“使命”人才计划(SML20150101);领军人才项目(Z141107001514002);科技北京百名领军人才培养工程北京学者(京人社专家发[2015]160号)


Changes of ocular arterial hemodynamics and the characteristics of intracranial carotid artery stenosis in patients with transient monocular vision loss
Author:
Affiliation:

Department of Medical Imaging, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
    摘要:

    目的 探讨短暂性单眼视野缺损眼部动脉血流动力学改变规律及颈内动脉狭窄的特点。 方法 采用回顾性病例对照研究。收集因短暂性单眼视野缺损(TMVL)就诊患者(共30例)的临床资料(TMVL组)。同时采集非视网膜缺血性病变的正常志愿者临床资料作为正常对照组。两组均行眼动脉、视网膜中央动脉、睫状后动脉超声检查,测量参数包括收缩峰流速、舒张峰流速、阻力指数及搏动指数,同时行头颈部CT血管成像检查,测量颈内动脉颅内段狭窄程度。 结果 TMVL组眼动脉收缩峰流速较正常对照组明显下降(28.40±3.69 cm/s比32.58±2.75 cm/s P=0.000),舒张峰流速较正常对照组明显下降(6.10±1.70 cm/s比7.35±1.49 cm/s,P=0.001);TMVL组视网膜中央动脉收缩峰流速较正常对照组明显下降(8.38±1.68 cm/s比9.92±2.30 cm/s,P=0.005),舒张峰流速较正常对照组明显下降(2.35±0.80 cm/s比2.88±0.62 cm/s,P=0.007);TMVL组睫状后动脉收缩峰流速较正常对照组收缩峰流速明显下降(10.01±2.25 cm/s比11.43±1.69 cm/s,P=0.008),舒张峰流速较正常对照组明显下降(3.30±1.16 cm/s比4.14±1.06 cm/s,P=0.006)。 TMVL组阻力指数、搏动指数在眼动脉、视网膜中央动脉及睫状后动脉较正常对照组均无统计学差异。TMVL组颈内动脉中、重度狭窄患者比例(约占63.33%)较正常对照组(10.00%)明显增高,差异有统计学意义(P=0.000)。 结论 TMVL患者较正常对照组眼部血流明显下降,而颈内动脉发生中、重度狭窄概率较正常对照组明显升高。

    Abstract:

    Aim To investigate the changes of ocular arterial hemodynamics in transient monocular vision loss (TMVL) and the characteristics of internal carotid artery stenosis. Methods Retrospective case control study was adopted. 30 patients’ clinical information diagnosed as TMVL was collected. At the same time, clinical data of normal volunteers was collected as control group. Ultrasonic examination of the ophthalmic artery, central retinal artery and posterior ciliary artery were used to detect peak systolic velocity (PSV), end of diastolic velocity (EDV), resistance index (RI) and pulsatility index(PI). Head and neck CTA was used to examine the stenosis of intracranial internal carotid artery. Results PSV of the ophthalmic artery was significantly decreased in TMVL group compared with the control group (28.40±3.69 cm/s vs 32.58±2.75 cm/s, P=0.000), EDV was significantly decreased in TMVL group compared with the control group (6.10±1.70 cm/s vs 7.35±1.49 cm/s, P=0.001). PSV of the central retinal artery was significantly decreased in TMVL group compared with the control group(8.38±1.68 cm/s vs 9.92±2.30 cm/s, P=0.005), EDV was significantly decreased in TMVL group compared with the control group(2.35±0.80 cm/s vs 2.88±0.62 cm/s, P=0.007). PSV of the posterior ciliary artery was significantly decreased in TMVL group compared with the control group(10.01±2.25 cm/s vs 11.43±1.69 cm/s, P=0.008),EDV was significantly decreased in TMVL group compared with the control group(3.30±1.16 cm/s vs 4.14±1.06 cm/s, P=0.006). There was no significant difference in the RI and PI of the TMVL group in the ophthalmic artery, the central retinal artery and the posterior ciliary artery, compared with the normal control group. The proportion of patients with moderate or severe stenosis of internal carotid artery was significantly higher in TMVL group than that of control group (63.33% vs 10.00%,P=0.000). Conclusion The ocular blood flow is significantly lower in TMVL group than that of the control group. The probability of carotid stenosis is significantly higher in TMVL group than that of the control group.

    参考文献
    相似文献
    引证文献
引用本文

李瑞,张伶,张鹏,赵鹏飞,王振常.短暂性单眼视野缺损眼部动脉血流动力学改变及颅内段颈内动脉狭窄特点[J].中国动脉硬化杂志,2018,26(3):260~264.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
历史
  • 收稿日期:2017-08-23
  • 最后修改日期:2017-12-01
  • 录用日期:
  • 在线发布日期: 2018-04-03