血管回声跟踪技术评价类风湿性关节炎患者颈动脉粥样硬化发生的临床研究
作者:
作者单位:

(1.衡水市哈励逊国际和平医院超声科,河北省衡水市 053000;3.衡水市哈励逊国际和平医院风湿免疫科,河北省衡水市 053000;2.衡水市第四人民医院超声科,河北省衡水市 053000)

作者简介:

孟令茜,主治医师,研究方向为妇产、血管,E-mail为hbmenglingqian@126.com。

基金项目:

衡水市科技计划项目(2016014109Z)


Clinical research on the evaluation of carotid atherosclerosis in patients with rheumatoid arthritis by vascular echo tracking technique
Author:
Affiliation:

1.Department of Ultrasound, ;3.Department of Rheumatology and Immunology, Harrison International Peace Hospital, Hengshui, Hebei 053000, China;2.Department of Ultrasound, the Forth People’s Hospital in Hengshui, Hengshui, Hebei 053000, China)

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    摘要:

    目的 探讨血管回声跟踪(ET)技术评价类风湿性关节炎(RA)患者颈动脉粥样硬化的发生。 方法 选择2016年1月至2017年5月在本院就诊的110例RA患者(试验组)进行研究,以同期在本院进行体检的健康人员100例作为对照组。采用血管ET技术测量两组研究对象的弹性模量(Ep)、僵硬度(β)、单点脉搏波传导速度(PWVβ)、膨大指数(AI)、动脉顺应性(AC)等颈动脉弹性参数;检查两组研究对象的颈动脉内膜中膜厚度(IMT)及斑块情况。 结果 试验组的Ep、β、PWVβ及AI等指标均明显高于对照组,而AC明显低于对照组,差异具有统计学意义(P<0.05)。试验组的颈动脉IMT明显高于对照组(P<0.05)。试验组颈动脉粥样硬化斑块的比率(4.55%)明显高于对照组(0.00%)(χ2=4.656,P=0.031)。 结论 在血管壁形态、结构尚未出现影像学特征改变之前,采用血管ET技术评估RA患者颈动脉弹性参数的变化,可以反映血管弹性状况,为预防RA患者颈动脉粥样硬化的发生提供帮助。

    Abstract:

    Aim To evaluate the occurrence of carotid atherosclerosis in patients with rheumatoid arthritis (RA) by vascular echo tracking (ET) technique. Methods From January 2016 to May 7,0 RA patients (test group) in our hospital were selected, and 100 healthy persons for physical examination in the same period were selected as control group. Carotid elastic parameters, such as pressure-strain elastic modulus (Ep), stiffness parameter (β), one-point pulse wave velocity (PWV beta), augmentation index (AI) and arterial compliance (AC) were measured by vascular ET technology in the two groups. Carotid intima-media thickness (IMT) and plaque conditions were examined in the two groups. Results The indexes of Ep, β, PWVβ and AI in the test group were significantly higher than those in the control group, while the AC in the test group was significantly lower than that in the control group; The differences were statistically significant (P<0.05). The carotid IMT in the test group was significantly higher than that in the control group (P<0.05). The ratio of carotid atherosclerotic plaque in the test group (4.55%) was significantly higher than that in the control group (0.00%) (χ2=4.656, P=0.031). Conclusion Before the imaging features change of vascular wall morphology and structure, vascular ET technology can be used to evaluate the changes of carotid elasticity parameters in RA patients, which can reflect the condition of vascular elasticity and provide help for preventing carotid atherosclerosis in RA patients.

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孟令茜,郭迎春,高志云,马星,刘文瑞,杨漪,彭肖.血管回声跟踪技术评价类风湿性关节炎患者颈动脉粥样硬化发生的临床研究[J].中国动脉硬化杂志,2018,26(3):287~290.

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  • 收稿日期:2017-06-23
  • 最后修改日期:2017-09-12
  • 在线发布日期: 2018-04-03