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炎症因素在自身免疫性疾病与动脉粥样硬化中的研究进展
作者:
作者单位:

(昆明医科大学第六附属医院医学检验科,云南省玉溪市 653100)

作者简介:

毕千叶,硕士,研究方向为炎症因子与动脉粥样硬化,E-mail为bqy588064@163.com。通信作者冯磊,博士,主任技师,博士研究生导师,研究方向为心脑血管疾病实验室诊断,E-mail为fngj2004@163.com。

基金项目:

国家自然科学基金地区科学基金项目(82160402)；云南省医学领军人才培养专项经费资助(L-2019022)


Research progress on the association of inflammatory factors in the pathogenesis of autoimmune diseases and atherosclerosis
Author:
Affiliation:

Department of Medical Laboratory, the Sixth Affiliated Hospital of Kunming Medical University, Yuxi, Yunnan 653100, China)

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    摘要:

    动脉粥样硬化是许多重要的血管不良事件的基础,严重威胁着人类健康。近年来,炎症及免疫调节因素在动脉粥样硬化发生发展中的作用越来越为人们所重视,自身免疫性疾病患者心血管病变的风险较常人显著提高,提示自身免疫性疾病与心血管疾病之间可能存在相互作用。文章通过检索国内外相关文献,综述了炎症因素在自身免疫性疾病与动脉粥样硬化中的作用及其相关机制,以期为防治自身免疫性疾病与动脉粥样硬化提供新思路。

    Abstract:

    Atherosclerosis is the basis of many important adverse vascular events, which seriously threatens human health. In recent years, more and more attention has been paid to the role of inflammatory and immune regulatory factors in the occurrence and development of atherosclerosis. It has been noted that the risk of cardiovascular disease in patients with autoimmune diseases is significantly higher than that in ordinary people. It is speculated that there may be a relationship between autoimmune diseases and the pathogenesis of cardiovascular disease cross. Therefore, this paper reviews the mechanism of autoimmune diseases and As by searching the relevant literature at home and abroad, in order to provide new ideas for the prevention and treatment of autoimmune diseases complicated with cardiovascular disease.

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    引证文献
引用本文

毕千叶,冯磊,马琦欣,邵聪,骆贝贝.炎症因素在自身免疫性疾病与动脉粥样硬化中的研究进展[J].中国动脉硬化杂志,2022,30(5):437~441.

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  • 收稿日期:2021-04-01
  • 最后修改日期:2021-11-08
  • 在线发布日期: 2022-05-10

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