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EECP对冠心病PCI术后患者血脂、血细胞计数衍生的炎症标志物及运动功能的影响
作者:
作者单位:

(1.山西医科大学第二医院心血管内科,山西省太原市 030000;2.天津市第三中心医院,天津市 300000)

作者简介:

李纪宁,硕士研究生,研究方向为动脉粥样硬化与动脉硬化,E-mail:lijining2017@163.com。通信作者申晓彧,博士,教授,研究方向为动脉粥样硬化与动脉硬化,E-mail:shenxy65@sina.com。

基金项目:

山西省自然科学基金面上项目(20210302123276)


The effect of EECP on blood lipids, blood count-derived inflammatory markers and exercise function in patients with coronary heart disease after PCI
Author:
Affiliation:

1.Department of Cardiovascular, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030000, China;2.Tianjin Third Central Hospital, Tianjin 300000, China)

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    摘要:

    目的]探讨在规范药物治疗前提下,联合增强型体外反搏(EECP)治疗对冠心病经皮冠状动脉介入治疗(PCI)术后患者血脂、炎症状态及心肺运动功能的影响。 [方法]选取2022年6月—2023年12月就诊于山西医科大学第二医院心血管内科并诊断为冠心病实行PCI术的患者93例,参照患者治疗意愿将其分为对照组及EECP组,对照组采取单纯药物治疗,EECP组在药物治疗的基础上联合EECP治疗3个月。记录并对比治疗前后的血脂、单核细胞/高密度脂蛋白胆固醇比值(MHR)、中性粒细胞/淋巴细胞比值(NLR)及运动耐量指标。 [结果]治疗后,EECP组患者总胆固醇(TC)下降19.6%,甘油三酯下降27.0%,低密度脂蛋白胆固醇(LDLC)下降25.0%,MHR下降25.4%,NLR下降37.2%,最大运动时间增加6.7%,差异有统计学意义(P＜0.05),效果优于对照组。 [结论]在规范药物治疗的基础上,冠心病PCI术后患者联合EECP治疗可有效降低血脂水平、改善全身炎症、促进运动功能的提升,改善患者生活质量。

    Abstract:

    Aim To investigate the effect of combined enhanced exteral counterpulsation (EECP) therapy on blood lipids, inflammatory status, and cardiorespiratory function in patients with coronary heart disease (CHD) after percutaneous coronary intervention (PCI), under the premise of standardized drug treatment. Methods A total of 93 patients diagnosed with CHD and undergoing PCI surgery at Cardiovascular Department, the Second Hospital of Shanxi Medical University were selected for screening from June 2022 to December 2023. According to the patients' treatment intention, they were randomly divided into control group and EECP group. The control group received simple drug treatment, while the EECP group received combined EECP treatment for 3 months on the basis of drug treatment. Blood lipids, monocyte to high density lipoprotein cholesterol ratio (MHR), neutrophil to lymphocyte ratio (NLR), and exercise endurance indicators were recorded and compared before and after treatment. Results After treatment, the patients in EECP group showed a 19.6% decrease in total cholesterol (TC), a 27.0% decrease in triglyceride (TG), a 25.0% decrease in low density lipoprotein cholesterol (LDLC), a 25.4% decrease in MHR, a 37.2% decrease in NLR, and a 6.7% increase in maximum exercise time, with statistical significance (P＜0.05). The treatment effect was better than that of the control group. Conclusion On the basis of standardized drug treatment, the combination of EECP treatment in patients with CHD after PCI can effectively reduce blood lipid levels, improve systemic inflammation, promote the improvement of motor function, and improve patients' quality of life.

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李纪宁,李露,申晓彧. EECP对冠心病PCI术后患者血脂、血细胞计数衍生的炎症标志物及运动功能的影响[J].中国动脉硬化杂志,2024,32(12):1062~1066.

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  • 收稿日期:2024-08-30
  • 最后修改日期:2024-10-10
  • 在线发布日期: 2025-01-06

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